Unico and Ergowear work very well for me. I used to have troubles catching my balls on the inseam of my pants/jean when I sat down and wrack myself. These underwear have the support and the size to help avoid this from happening. There are other brands of underwear that offer the size and support, but these generally fit me very well and are good quality. I've been wearing both brands plus a couple N2N styles for over three years and am very happy with them.

I hope this is helpful.