huge sci fi geek, so surprised i haven't tripped on this thread before. for my money, here are my tops:
Serenity Donnie Darko Children of Men Eternal Sunshine of the Spotless Mind Empire Strikes Back Star Wars Return of the Jedi The Matrix Fifth Element even numbered Star Trek films Star Trek: First Contact Ghostbusters Back to the Future ET Close Encounters of a Third Kind Jurassic Park Brazil 12 Monkeys Terminator T2 Men in Black Blade Runner Alien Aliens Alien 3 The Iron Giant Adventures of Buckaroo Banzai Across the 8th Dimension Independence Day Pitch Black
(yes, i do enjoy some cheese with my sci-fi from time to time.

)
for sci fi TV:
Firefly Battlestar Galactica (current) Lost Doctor Who Cowboy Bebop Star Trek Star Trek: The Next Generation Star Trek: Deep Space Nine Heroes The 4400 Futurama
just to name a few.
as for graphic novels being adapted soon,
Y the Last Man seems on the fast track. Neil Gaiman is apparently well on the way to getting his adaptation of his own
Death: The High Cost of Living made.
Hellboy sequel coming soon, and i'm so psyched about that! and of course the long awaited (and in some circles slightly dreaded) adaptation of Alan Moore and Dave Gibbons'
Watchmen, which i'm hoping will be good. oh, and
The Dark Knight which looks excellent. i think those are the only ones in development that i'm really looking forward to right now. oh, and Brian Michael Bendis'
Jinx is supposedly still coming out at some point with Charlize Theron as the title character...and Mark Millar's
Wanted, though some of what i've heard makes a bit hesitant towards it. we'll see. Grant Morrison and Frank Quitely's
We3 has been optioned by New Line, i believe...but i think they're still drafting a screenplay.